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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCNX
All Species:
14.55
Human Site:
S680
Identified Species:
26.67
UniProt:
Q96RV3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RV3
NP_055797.2
2341
258676
S680
R
A
T
R
R
T
S
S
T
N
S
A
K
T
R
Chimpanzee
Pan troglodytes
XP_510039
2300
254005
P674
M
A
P
E
S
I
K
P
L
T
T
S
K
S
D
Rhesus Macaque
Macaca mulatta
XP_001084081
2342
258864
S681
R
A
T
R
R
T
S
S
T
N
S
A
K
T
R
Dog
Lupus familis
XP_537501
2332
257280
L684
T
R
A
R
V
L
S
L
D
S
G
T
V
A
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYC1
2344
258128
S683
R
A
S
R
R
T
S
S
T
S
S
A
K
T
R
Rat
Rattus norvegicus
NP_001163818
2343
257924
S682
R
A
S
R
R
T
S
S
T
H
S
A
K
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423893
2312
255194
K677
I
K
Q
L
T
T
S
K
S
D
L
E
A
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923995
2285
252748
R678
D
A
A
S
L
L
G
R
A
S
Q
L
E
S
V
Tiger Blowfish
Takifugu rubipres
Q98UF7
1703
191329
G122
R
E
D
S
N
G
L
G
D
P
G
G
G
I
E
Fruit Fly
Dros. melanogaster
P18490
3433
367590
L949
Q
I
L
Q
R
C
Q
L
D
E
E
Q
P
C
T
Honey Bee
Apis mellifera
XP_624687
2092
236172
T510
I
D
D
N
I
T
I
T
E
Q
T
R
H
K
L
Nematode Worm
Caenorhab. elegans
NP_492790
1634
183268
R53
T
V
Q
L
P
L
T
R
R
E
R
A
L
S
S
Sea Urchin
Strong. purpuratus
XP_001195494
2799
311472
V728
V
A
P
D
G
T
V
V
S
N
R
L
L
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
98.7
94.4
N.A.
90.9
91.1
N.A.
N.A.
84.9
N.A.
66.7
54.4
29.4
38.7
27.7
35.5
Protein Similarity:
100
98.1
99.4
96.4
N.A.
95.5
95.3
N.A.
N.A.
90.8
N.A.
77.7
63
42.9
55.5
41.8
49.2
P-Site Identity:
100
13.3
100
13.3
N.A.
86.6
86.6
N.A.
N.A.
13.3
N.A.
6.6
6.6
6.6
6.6
6.6
20
P-Site Similarity:
100
33.3
100
20
N.A.
100
100
N.A.
N.A.
26.6
N.A.
26.6
6.6
20
20
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
16
0
0
0
0
0
8
0
0
39
8
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% C
% Asp:
8
8
16
8
0
0
0
0
24
8
0
0
0
0
8
% D
% Glu:
0
8
0
8
0
0
0
0
8
16
8
8
8
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
8
8
8
0
0
16
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
16
8
0
0
8
8
8
0
0
0
0
0
0
8
0
% I
% Lys:
0
8
0
0
0
0
8
8
0
0
0
0
39
16
8
% K
% Leu:
0
0
8
16
8
24
8
16
8
0
8
16
16
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
24
0
0
0
0
0
% N
% Pro:
0
0
16
0
8
0
0
8
0
8
0
0
8
0
0
% P
% Gln:
8
0
16
8
0
0
8
0
0
8
8
8
0
0
0
% Q
% Arg:
39
8
0
39
39
0
0
16
8
0
16
8
0
0
31
% R
% Ser:
0
0
16
16
8
0
47
31
16
24
31
8
0
31
8
% S
% Thr:
16
0
16
0
8
54
8
8
31
8
16
8
0
31
8
% T
% Val:
8
8
0
0
8
0
8
8
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _